Objective To systematically evaluate the qualitative research on the care experience of home hospice caregivers,in order to provide references for paying attention to the care quality of home caregivers and building a home hospice care support system. Methods Qualitative studies on the nursing experience of home hospice caregivers were searched in electronic databases,including the Cochrane Library,JBI,Embase,PubMed,PsycINFO,Web of Science,CINAHL,CNKI,WanFang,CBM Database. The search time was from inception to June 31,2021. Quality of the literature were evaluated according to JBI Critical Appraisal Checklist for Qualitative Research and then the meta-synthesis was performed. Results Totally 19 studies were included and 80 research results were extracted. Finally 7 categories and 3 integrated results were formed. Integrated result：①Caregivers have strong negative experience;②Caregivers actively respond to negative experiences and gain personal growth;③Caregivers seek multifaceted support. Conclusion Home hospice caregivers have heavy care burden and great physical and mental pressure,and are eager for multi-party support. It is suggested to pay attention to the inner experience and needs of family caregivers,and build a regional homogeneous linkage support system of home hospice,so as to improve the nursing quality of home hospice.